One of the most critical components of Faro’s approach

One of the most critical components of Faro’s approach involves using a structured definition of the clinical study in question as the foundation for the protocol document. Without such a structured representation of the study, including the Schedule of Activities, generating a complete and high-quality protocol document would be impossible. To accomplish this, Faro leverages our Study Designer, which empowers study teams to design protocols with the benefit of collaborative tools and data-driven insights. Beyond simply representing the SoA in a machine-readable format, the study definition also, critically, contains rich details about each assessment and measurement, without which it would be challenging to provide the level of granularity required by many sections of the M11 template. Thus, any clinical protocol document we aim to generate starts with a data-backed foundation built within Faro’s Study Designer

• Generate the initial prompts

Today’s LLMs are especially sensitive to the structure and content of the prompts they are given. Faro has explored a wide variety of prompt options, and identified an approach that results in the most reliable and flexible initial output. This involves asking the LLM to generate sections or subsections of the protocol individually, rather than generating the entire document at once. By generating sections individually, we can better represent the requirements of each individual section or subsection, and be set up to evaluate each section against the most appropriate rubric. Furthermore, by working in sections, this approach enables users to regenerate or modify individual sections, resulting in significant savings in compute time and cost for each iteration.

One of the most critical components of Faro’s approach involves using a structured definition of the clinical study in question as the foundation for the protocol document. Without such a structured representation of the study, including the Schedule of Activities, generating a complete and high-quality protocol document would be impossible. To accomplish this, Faro leverages our Study Designer, which empowers study teams to design protocols with the benefit of collaborative tools and data-driven insights. Beyond simply representing the SoA in a machine-readable format, the study definition also, critically, contains rich details about each assessment and measurement, without which it would be challenging to provide the level of granularity required by many sections of the M11 template. Thus, any clinical protocol document we aim to generate starts with a data-backed foundation built within Faro’s Study Designer

• Generate the initial prompts

Today’s LLMs are especially sensitive to the structure and content of the prompts they are given. Faro has explored a wide variety of prompt options, and identified an approach that results in the most reliable and flexible initial output. This involves asking the LLM to generate sections or subsections of the protocol individually, rather than generating the entire document at once. By generating sections individually, we can better represent the requirements of each individual section or subsection, and be set up to evaluate each section against the most appropriate rubric. Furthermore, by working in sections, this approach enables users to regenerate or modify individual sections, resulting in significant savings in compute time and cost for each iteration.

One of the most critical components of Faro’s approach involves using a structured definition of the clinical study in question as the foundation for the protocol document. Without such a structured representation of the study, including the Schedule of Activities, generating a complete and high-quality protocol document would be impossible. To accomplish this, Faro leverages our Study Designer, which empowers study teams to design protocols with the benefit of collaborative tools and data-driven insights. Beyond simply representing the SoA in a machine-readable format, the study definition also, critically, contains rich details about each assessment and measurement, without which it would be challenging to provide the level of granularity required by many sections of the M11 template. Thus, any clinical protocol document we aim to generate starts with a data-backed foundation built within Faro’s Study Designer

• Generate the initial prompts

Today’s LLMs are especially sensitive to the structure and content of the prompts they are given. Faro has explored a wide variety of prompt options, and identified an approach that results in the most reliable and flexible initial output. This involves asking the LLM to generate sections or subsections of the protocol individually, rather than generating the entire document at once. By generating sections individually, we can better represent the requirements of each individual section or subsection, and be set up to evaluate each section against the most appropriate rubric. Furthermore, by working in sections, this approach enables users to regenerate or modify individual sections, resulting in significant savings in compute time and cost for each iteration.